HEAT-Net Meeting 2024

Frontiers in Neurodegeneration: from bench to bedside

 

Thursday September 5^th

8:30 Coffee

 

9:00-9:10: Welcome from the organizing Committee, Dr. Manuel Rosety Dean of Medicine School from the University of Cadiz and the ViceChancellor of Research from the University of Cadiz.

 

Session 1 – Biomarkers for prediction and diagnostics

9:10-9:30: Christina Lill: Prediction of neurodegenerative diseases in the longitudinal EPIC cohort using a multi-omics approach

9:30-9:50: Alberto Lleó: Update on blood biomarkers in Alzheimer’s disease

9:50-10:10: Henrik Zetterberg: Update on biofluid-based biomarkers for non-Alzheimer’s neurodegenerative dementias

 

10:10-10:30 Discussion

 

Session 2 – What is new in genetics?

10:30-10:50: Lars Bertram: The role of short tandem repeats in Alzheimer’s disease genetics

10:50-11:10: Mikko Hiltunen: Functional characterization of Alzheimer’s disease-associated genetic variants in NPH biopsy samples

 

11:10-11:30: Discussion

 

Session 3 – Animal models for neurodegeneration

11:30-11:50: Christine von Arnim: Cognitive impairment in an obesity mouse model

11:50-12.10: Monica Garcia-Alloza: Blood-brain barrier and blood-retina barrier in AD- diabetes models

12:00-12:30: Clevio Nobrega: New players and targets in neurodegeneration: the case of spinocerebellar ataxias

 

12:30-12:50: Discussion

 

12:50-15:15: Poster session and Lunch

 

Session 4 – Brief talks

15.15-16.15: Brief talks by junior investigators

 

Session 5 – Keynote lecture

16.15-17.00: Brad Hyman: Testing assumptions about neurodegeneration in AD

17.00-17.15: Discussion

 

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Friday September 6^th

8:30: Coffee

 

Session 6 – Propagation and aggregation in neuroinflammation and neurodegeneration

9:00-9:20: Karin Danzer: Propagation mechanisms in PD and ALS models

9:20-9:40: Tiago Outeiro: Modeling and imaging protein aggregation in cells

9:40-10:00: Cintia Roodveldt: Novel signaling mechanisms in microglia-mediated neuroinflammation and implications for neurodegenerative diseases.

 

Session 7 – Synaptic pathology in neurodegeneration

10:00-10:20: Anna-Kaisa Haapasalo: Synaptic disturbances in frontotemporal dementia

10:20-10:40: Tara Spires-Jones: Synaptic tau – a tangled issue

10:40-11:00: Rafael Fernandez Chacon: Molecular pathophysiology of a synaptic co-chaperone in neurodegeneration

 

11:00-11:20: Discussion

 

Session 8 – Brief talks

11.20-12.30: Brief talks by junior investigators

 

12.30-15.00: Poster session and Lunch

 

Session 9 – Novel therapies

15:00-15:20: Martin Ingelsson: Development of immunotherapy for Parkinson’s disease

15:20-15:40: Teresa Gomez-Isla: New era and new challenges in the treatment of Alzheimer’s disease

 

15:40-16.00: Discussion

 

Session 10 – Keynote lecture

16:00-16:45: Brian Bacskai: In vivo imaging of cell and organelle specific pathophysiology in a mouse model of Alzheimer’s disease

16:45-17:05: Discussion

 

20:00: Dinner